I would say that Bitcoin is the safest mode of payment gateway for online payments.
I know of no "legit" business that insists on paying their vendors or service providers in Bitcoin
We maybe see 1-2% of our clients use Bitcoin. Meh, just another payment option.
Indeed most providers probably get Paypal/credit cards payments the most. But being more accessible does not hurt when it real viable option.
Problem with offering payment options that are not that used is you end up with one client who pays through it lets say $4 a month for shared hosting and the withdraw fees become very high because you have very little volume on that gateway
In that case I would keep that gateway's balance as a "backup" funding solution. Then you need a "little boost" hey you got something right? With Bitcoins you could even get more in "real cash" value to get more than that $4. In fact that why a provider stated why they openly accept Bitcoins.
Money is Money. Accept it however you can!
Just my two cents.
Even when it costs you more to withdraw it?
Well, Now every other firm online is accepting BitCoin.