It's the thought of having thousands of invisible people listening to my every word that freaks me out. I'd probably prefer presenting at an actual conference, as I'd be able to see the people reacting to my every (stuttered) word. My imagination will be the death of me.
Anyways, thank you for all of the advice. Even though I in no way intend to ever speak in front of a large audience, at least now I have some (albeit minor) motivation if the situation shall ever arise.
The one thing to keep in mind is that all those people who are listening to you are essentially no different than you. They're not out to get you, rather they're tuning in for info, and if what you're talking about provides them the info they're looking for - you're good to go.