I'm not new to hosting business but my current company is new, started in Jan 2015, being from India I had limited options so i opted for PayPal and 2CO. My PayPal account is again more then 10 years old was in use my other company as well, but i got 2CO account to accept credit card payments as well. I had no chargebacks or any other complains but then one day some fraud user tried to order with us with multiple cards or tried multiple times and none of the payments went through, that fraud tried like 10-15 times but being a new company these attempts reached 30% of total number of transactions per month (As i mentioned we were a new company so did not had many Credit Card Transactions, mostly Paypal, BTC etc...)
Now as i said not a single chargeback, just some fraud tried fraudulent credit cards and 2CO closed our account
So this is something that you can come across, especially if you are new and don't have too many transactions.
Though now we have incorporated our company in Singapore and have got account with Stripe and soon with Worldpay or BrainTree as we need 3D Secure