The two favourites of mine are Chicago and Dallas. They seem to be the best in terms of connectivity and latency. Amsterdam is especially good if you're looking for a EU location
It is very important to see where your traffic go through and major customer requirement. there is no point to select a dc which is tier 4 rank, but network might give you longer latency.
Central US (Chicago / Dallas) would be my first choice, assuming what is being hosted wasn't meant to service a majority in a specific location that was latency sensitive.
I'm an East Coast person as well. I see a lot of providers offer in Scranton PA, which is where I live. Always got me wondering if they are talking about Burst.net which again is only a stones throw away from me.