cPanel and Plesk dual it out on a regular basis, and there's a few others that pop up to proclaim that they operate with a lower memory overhead and less CPU usage etc. I've been a fan of cPanel for many many years (10 maybe), and I'd not personally change to another control panel any time soon. Our clients love it, it's easy for our admins to use, and it's what we're comfortable with. Price is not overly expensive and for what it does, it's worth every penny.
I don't see cPanel being knocked off any time soon as a usable choice, but I don't see many end users seeking out a host that must have cPanel - their main concern is uptime.