I think this relies on a few things.
What qualifies as best may be different from different point of views. For example, I generally have people who are new to the industry who are overwhelmed by panels with excessive amounts of options.
Then we have those who are veterans who can navigate hundreds of options and addons with ease.
I find that custom skins often help here, where users can change what is shown and available at their own will. Also, having a good guide or structured tutorial site can help guide customers. This can be unique to what you are selling or you can point them to those already created by the developers.
Automating things such as backups, updates and notification management can lift a huge strain off of customers who are new to the hosting world.