Having used and offered Fantastico for 9 years, in 2010 we swapped completely to Softaculous and haven't looked back. Fantastico was very slow for updates (even critical patches) whereas Softaculous has an update within hours or a day of any major patches. I don't think Fantastico ever did cross the 50 script mark, but Softaculous is approaching nearly 200 scripts that can install.
Price shouldn't even be a concern as your clients will just eat up the ability to install so many scripts. We don't charge anything for the use of Softaculous on our shared hosting setups - it's been a pleasure and a breeze to use! A few license issues pop up from time to time when the systems don't sync correctly, but beyond that, it's been great to work with.