We use CSF and LFD on all our servers at Hands-on - including Clustered Servers and Cloud Setups - no issues. I don't remember any of our staff having to make any tweaks to the software to make it run - it was just a regular install and away it went.
to get it to run in clustered mode, you do indeed need to setup the cluster feature in csf and turn it on, it's pretty straight forward once you go through the csf config file
joe