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HPE brings Nvidia Blackwell power, agentic AI to enterprises

HPE has rolled out significant enhancements to its Nvidia-based AI lineup, integrating more advanced, agent-like AI features with hardware engineered for today’s high-intensity workloads. In short, they’re upping the ante for organizations needing serious computational power for modern AI applications. The latest release strengthens HPE Private Cloud AI, developed with Nvidia, by weaving in the chipmaker’s newest AI stack.

The update adds Nvidia’s Llama Nemotron reasoning models, which let AI agents operate efficiently across a range of environments, from edge devices to multi-GPU servers. These models integrate with Nvidia’s inference microservices, giving enterprises ready-made building blocks for AI-driven workflows. HPE also brought in Nvidia Cosmos Reason, a vision-language model designed for robotics and other computer vision uses, including autonomous vehicles.

The shift toward agentic AI is already influencing infrastructure strategies. Cisco recently warned that widespread AI agent adoption could strain network capacity on a massive scale. At the same time, other tech firms are releasing tools to visualize and manage these AI-powered systems. HPE has added its own agentic AI management features to GreenLake to help teams diagnose network issues, a development created separately from Nvidia’s efforts.

On the hardware front, HPE introduced Nvidia’s Blackwell architecture to its ProLiant servers for the first time. The new DL385 Gen11 model supports up to two RTX PRO 6000 Blackwell Server Edition GPUs in a 2U configuration for air-cooled data centers. The larger DL380a Gen12 can scale to eight GPUs for heavy inferencing and vision workloads. Both systems are equipped with HPE’s iLO 7 management chip—it’s essentially the hardware backbone for security. You’ve got a silicon root of trust, secure enclaves for isolating sensitive workloads, and firmware signing designed to withstand even quantum-level threats.

These enhancements mean IT teams can roll out AI workloads with serious performance, all while keeping their existing security models intact. HPE and Nvidia are pushing a solution where hardware-level protections work hand-in-hand with scalable AI infrastructure. The goal? Enterprises get robust tools for handling AI’s complexity, but they don’t have to sacrifice control, speed, or trust in the process.

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