I currently use R1Soft but whilst it is good, I have been trying to migrate to Acronis, it's just a little more complicated than R1Soft but I'll definitely have to update this post or make a new thread when I know which path I choose
Odd. I found the opposite! Acronis is fiddly to use when using self-hosted Acronis Backup as you have to use Acronis Cyber Infrastructure and meet the hardware requirements, which is more complex and requires a bigger investment.
Because of that, I prefer to use Acronis Backup Cloud, so the data is hosted in the Cloud within their UK datacentre. Far fewer problems that way. I don't have to worry about the hardware/network side of things then. Let Acronis take care of it.
Acronis works great with cPanel. There have been some slight issues with the integration since I started using it a few years ago, but that can be said for anything. Happy enough with it now. I recommend using Acronis + JetBackup to be on the safe side.